Nonlinear bioavailability of metoclopramide in the rat: evidence for saturable first-pass metabolismKAPIL, R. P; AXELSON, J. E; ONGLEY, R et al.Journal of pharmaceutical sciences. 1984, Vol 73, Num 2, pp 215-218, issn 0022-3549Article

Rectal, oral and I. A. administration of etomidate to rats : significant avoidance of hepatic first-pass elimination following rectal administrationDE BOER, A. G; BREIMER, D. D.Archives internationales de pharmacodynamie et de thérapie. 1984, Vol 270, Num 2, pp 180-191, issn 0003-9780Article

Metabolic first-pass effectsPANG, K. S.Journal of clinical pharmacology. 1986, Vol 26, Num 8, pp 580-582, issn 0091-2700Article

A new model-independent physiological approach to study hepatic drug clearance and its applicationsCHIOU, W. L.International journal of clinical pharmacology, therapy and toxicology (1980). 1984, Vol 22, Num 11, pp 577-590, issn 0174-4879Article

Probability of failure in Random vibrationNIELSEN, S. R. K; SORENSEN, J. D.Journal of engineering mechanics. 1988, Vol 114, Num 7, pp 1218-1230, issn 0733-9399Article

The role of metabolites in bioequivalency assessment. II: Drugs with linear pharmacokinetics and first-pass effectMEI-LING CHEN; JACKSON, A. J.Pharmaceutical research. 1995, Vol 12, Num 5, pp 700-708, issn 0724-8741Article

Theoretical considerations in the calculation of bioavailability of drugs exhibiting Michaelis-Menten elimination kineticsRUBIN, G. M; TOZER, T. N.Journal of pharmacokinetics and biopharmaceutics. 1984, Vol 12, Num 4, pp 437-450, issn 0090-466XArticle

Mean hepatic transit time in the determination of mean absorption timeCHIOU, W. L.Journal of pharmaceutical sciences. 1983, Vol 72, Num 11, pp 1365-1368, issn 0022-3549Article

Distribution of mean first-passage times in random chains due to disorderKEHR, K. W; MURTHY, K. P. N.Physical review. A, General physics. 1990, Vol 41, Num 10, pp 5728-5730, issn 0556-2791Article

Effect of allopurinol on the first-pass metabolism of 6-mercaptopurine in the ratSASAKI, H; TSURU, K; NAKAMURA, J et al.Biochemical pharmacology. 1987, Vol 36, Num 23, pp 4175-4176, issn 0006-2952Article

Glucuronidation in the rat intestinal wallKOSTER, A. S; MEEWISSE, C. P. J; FRANKHUIJZEN-SIEREVOGEL, A. C et al.Biochemical pharmacology. 1985, Vol 34, Num 3, pp 421-422, issn 0006-2952Article

Pharmacokinetics of triamterne after i.v. administration to man: determination of bioavailabilityGILFRICH, H. J; KREMER, G; MOHRKE, W et al.European journal of clinical pharmacology. 1983, Vol 25, Num 2, pp 237-241, issn 0031-6970Article

Pharmacokinetic approach to the estimation of hepatic removal of insulinBERZINS, R; TAM, Y. K; MOLNAR, G. D et al.Pancreas. 1986, Vol 1, Num 6, pp 544-549, issn 0885-3177Article

Effects of d,l-verapamil on atrioventricular conduction in relation to its stereoselective first-pass metabolismECHIZEN, H; VOGELGESANG, B; EICHELBAUM, M et al.Clinical pharmacology and therapeutics. 1985, Vol 38, Num 1, pp 71-76, issn 0009-9236Article

First pass metabolism of ethanol ― A gastrointestinal barrier against the systemic toxicity of ethanolJULKUNEN, R. J. K; DI PADOVA, C; LIEBER, C. S et al.Life sciences (1973). 1985, Vol 37, Num 6, pp 567-573, issn 0024-3205Article

A deconvolution method for estimating the first-pass metabolism of orally administered drugsYAMASHITA, F; BANDO, H; TAKAKURA, Y et al.Biological & pharmaceutical bulletin. 1995, Vol 18, Num 12, pp 1787-1789, issn 0918-6158Article

Physiologically based models and strategic experiments in hepatic pharmacologyBASS, L; KEIDING, S.Biochemical pharmacology. 1988, Vol 37, Num 8, pp 1425-1431, issn 0006-2952Article

Partial avoidance of first-pass elimination of azathioprine in rats by rectal dosingTAKADA, K; YOSHIKAWA, H; MURANISHI, S et al.International journal of pharmaceutics. 1985, Vol 25, Num 2, pp 155-163, issn 0378-5173Article

The pharmacokinetics of α-methyldopa in dogsKOCHAK, G. M; MASON, W. D.Journal of pharmacokinetics and biopharmaceutics. 1985, Vol 13, Num 4, pp 405-423, issn 0090-466XArticle

Comparison of the first-pass metabolism ethenzamide and salicylamide in ratsSHIBASAKI, U; KONISHI, R; TAKEMURA, M et al.Journal of pharmacobio-dynamics. 1984, Vol 7, Num 11, pp 804-810, issn 0386-846XArticle

Drug metabolite concentration-time profiles: influence of route of drug administrationHOUSTON, J. B; TAYLOR, G.British journal of clinical pharmacology. 1984, Vol 17, Num 4, pp 385-394, issn 0306-5251Article

Proceedings/NATO advanced study institute on pharmacokinetics: mathematical and statistical approaches to metabolism and distribution of chemicals and drugs, June 2-13, 1987, Erice, ITAPECILE, A; RESCIGNO, A.NATO ASI series. Series A : life sciences. 1988, Vol 145, issn 0258-1213, X-348 pConference Proceedings

First passage time for linear systems with stochastic coefficientsBERGMAN, L. A; SPENCER, B. F. JR.Probabilistic engineering mechanics. 1987, Vol 2, Num 1, pp 46-53, issn 0266-8920Article

Presystemic and systemic intestinal metabolism of fenoterol in the conscious ratKOSTER, A. S; HOFMAN, G. A; FRANKHUIJZEN-SIEREVOGEL, A. C et al.Drug metabolism and disposition. 1985, Vol 13, Num 4, pp 464-470, issn 0090-9556Article

Liquid chromatographic assay for promethazine in plasma using electrochemical detectionMELETHIL, S; DUTTA, A; CHUNGI, V et al.Analytical letters. 1983, Vol 16, Num 9, pp 701-709, issn 0003-2719Article